Secretary Rubio also intends to convey the U.S.'s desire to regain control over the Panama Canal. This objective faces strong opposition from regional leaders, suggesting potential diplomatic challenges during the visit. The agenda reflects the administration's assertive approach to foreign policy in the region.

The visit underscores the continued importance of Central America to U.S. foreign policy, particularly concerning immigration and strategic assets like the Panama Canal. The reactions to Secretary Rubio's visit, including the protests, highlight the complexities and sensitivities surrounding U.S. involvement in the region. The outcome of these discussions could significantly impact U.S.-Panama relations and broader regional dynamics.